Description
Retatrutide is an investigational peptide studied as a triple agonist for GLP-1, GIP, and glucagon receptors. It is a synthetic 39–amino acid peptide designed as a triple receptor agonist, showing activity at GIP, GLP-1, and glucagon receptors. These signaling pathways are actively studied for their roles in metabolic regulation, glucose control, appetite signaling, and energy expenditure.
Important Note
Retatrutide is not approved for human consumption, medical use, or diagnostic purposes. It is supplied strictly for laboratory research only. Handling should be performed by qualified professionals in an appropriate research setting.
| Form | Suggested Research
Concentration |
Example Preparation | Notes |
| Lyophilized Powder | 10 mg per vial | Reconstitute with sterile or
bacteriostatic water |
Store dry at –20°C until
use |
| Reconstituted Solution | 200–500 µg/mL | Dissolve to target concentration for
experiments |
Stable at 2–8°C for 2–3
weeks; do not freeze once reconstituted |
| Experimental
Dosing (animal studies, literature-based)* |
Variable by study | Adjust according to study design | Preclinical models only |
Storage & Stability
– Lyophilized peptide: Stable for up to 24 months at –20°C.
– Reconstituted solution: Stable for 2–3 weeks at 2–8°C.
– Avoid repeated freeze–thaw cycles.
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